• Coordinating research in the area of nutrition, diet, health and physical activity

    Coordinating research in the area of nutrition,
    diet, health and physical activity


    The Joint Programming Initiative a Healthy Diet for a Healthy Life (JPI HDHL)
    brings together 26 countries that align research programming and fund new research
    to prevent or minimise diet-related chronic diseases

OPEN CALL
ERA-HDHL (2019):
Food and Nutrition Security Knowledge Hub
Opening
29th of January 2019
Closing
18th of September 2019
(only for network members that have been selected)
  • Results of FOODBALL and MIRDIET
  • Results of FOODBALL and MIRDIET

    The two research projects that were funded under the JPI HDHL Joint Action “Biomarkers for Nutrition and Health” recently finished and the results are now available.

    Read more

CirculAting Bile Acids as biomarkers of metabolic health - Linking microbiotA, Diet and Health

WHAT: Bile acids (BA) through TGR5 and FXR regulate mammalian inflammation, lipid, glucose, and energy metabolism, and are in turn regulated by diet: microbe interactions in the gut. CABALA_DIET&HEALTH aims to establish circulating BA profiles as biomarkers of health, modulated by diet which reflect a change in metabolic health.

WHO: Partner (Coordinator): Kieran Tuohy, Fondazione Edmund Mach, Italy. Partner: Gianfagna Francesco, Università degli Studi dell'Insubria, Italy. Partner: Susan Joyce, University College Cork, Ireland. Partner: Julie Lovegrove, University of Reading, UK. Collaborator: Iris Shai, Ben-Gurion University of the Negev, Israel.

HOW: Using existing data and new mechanistic studies we will provide direct evidence in humans that diet: gut microbiota interactions modulate plasma BA profiles and modulate host health. Our aim is to identify plasma BA profiles as health biomarkers and establish microbiota modulation of BA signalling as a unifying molecular basis for efficacious probiotic, prebiotic and polyphenol functional foods.

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