5th International Conference of JPI HDHL on the 20th of February 2019

5th International Conference of JPI HDHL on the 20th of February 2019

The 5th international conference of the Joint Programming Initiative ‘A Healthy Diet for a Healthy...

ERA-HDHL “Nutrition & the Epigenome”: six projects recommended for funding

ERA-HDHL “Nutrition & the Epigenome”: six projects recommended for funding

The second non-cofunded action under ERA-HDHL focusses on the emerging field of nutrition &...

Joint JPIs Declaration presented at Austrian Presidency conference on 10 years Joint Programming

Joint JPIs Declaration presented at Austrian Presidency conference on 10 years Joint Programming

For 10 years, countries from Europe and beyond have been joining forces in Joint Programming...

Community-led working group @OBEDIS started

Community-led working group @OBEDIS started

In 2017 JPI HDHL launched a rapid action call to support a community-led working group that can...

  • 5th International Conference of JPI HDHL on the 20th of February 2019

  • ERA-HDHL “Nutrition & the Epigenome”: six projects recommended for funding

  • Joint JPIs Declaration presented at Austrian Presidency conference on 10 years Joint Programming

  • Community-led working group @OBEDIS started

Community-led working group @OBEDIS started

Community-led working group @OBEDIS started

In 2017 JPI HDHL launched a rapid action call to support a community-led working group that can...

Joint JPIs Declaration presented at Austrian Presidency conference on 10 years Joint Programming

Joint JPIs Declaration presented at Austrian Presidency conference on 10 years Joint Programming

For 10 years, countries from Europe and beyond have been joining forces in Joint Programming...

ERA-HDHL “Nutrition & the Epigenome”: six projects recommended for funding

ERA-HDHL “Nutrition & the Epigenome”: six projects recommended for funding

The second non-cofunded action under ERA-HDHL focusses on the emerging field of nutrition &...

Valerolactones and healthy Ageing: LInking Dietary factors, nutrient biomarkers, metabolic status and inflammation with cognition in older adults.

WHAT: Polyphenols, particularly procyanidins (abundant in foods such as tea, cocoa, grapes, nuts and berries), may be beneficial in maintaining better cognitive function in ageing, but investigating their role in relation to health is hampered by the lack of robust biomarkers of dietary intake. We will validate novel plasma biomarkers of procyanidin-rich foods and link them with inflammation, metabolic health and cognition in an ageing European population.

WHO: VALID brings together partners from the UK, Ireland and Italy with interdisciplinary expertise in nutrition, food bioactives, immunology, geography and clinical gerontology, with the aim of conducting impactful research linking dietary polyphenols with cognitive health in older adults. VALID builds on the Joint Irish Nutrigenomics Organisation (JINGO) project and specifically its component Trinity, Ulster, Department of Agriculture (TUDA) cohort study. The partners are Helene McNulty, Northern Ireland Centre for Food and Health, UK (Coordinator); Daniele Del Rio, University of Parma, Italy and Anne Molloy, Trinity College Dublin, Ireland.

HOW: VALID draws on the TUDA cohort, a unique resource on 5200 adults aged 60-102 years recruited from the UK and Ireland, providing a range of biomarkers and health measures. Apart from performing new analysis on bio-banked TUDA samples, we will access ‘TUDA 5+’, a follow-up study of 1000 participants from the original cohort 5 years after initial investigation, to determine the role of procyanidin-rich foods in preventing cognitive decline over a 5-year follow-up period.

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