Pregnancy and infancy are critical periods for nutritional programming of metabolic health. Epigenetic changes
seem to have a crucial role in pathways leading from early-life nutrition to metabolic health across the life course.
NutriPROGRAM will use knowledge and data infrastructures from different collaborative consortia including the
Horizon2020 DynaHEALTH and LifeCycle Projects, the ERA-HDHL ALPHABET project, and the Pregnancy
and Childhood Epigenetics (PACE) Consortium, which includes 40 studies with 30,000 samples with epigenomewide
DNA methylation data. Eventually, NutriPROGRAM will develop a sustainable, translational, international
collaboration for current and future studies on nutrition and epigenetics and their role in sustaining good health
throughout the life course.