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- Background and aimHEALTHMARK investigated the complex associations between diet, microbiota, tryptophan metabolites of microbial metabolism, and metabolic health in a set-up of identification, replication, and validation of associations. The project, organized in five work packages (WP) comprised two observational and two intervention studies.In WP1, the University of Bonn (UB) using the DOrtmund…
- Prevention of unhealthy weight gain in families in pregnancy and postpartum using a mHealth-enhanced intervention
- Innovative plant protein fibre and physical activity solutions to address poor appetite and prevent undernutrition in older adults
- Cardiovascular and metabolic diseases are a primary cause of morbidity and mortality worldwide. Diet is a major risk factor for cardio-metabolic health, but is challenging to study in part because metabolic response to diet is highly individualised. Characterising the molecular pathways that mediate personalised responses to diet is critical to effectively tackle the current epidemic. Epigenetic…
- An increased intestinal permeability (IP), also known as leaky gut, could be responsible for activation of the immune system and inflammation, a common mechanism in many chronic age-related diseases. The MaPLE project tested the hypothesis that an increased intake of polyphenol-rich foods can reduce IP and the quantity of inflammogenic bacterial factors in the bloodstream, promoting a protective…
